FEATURES OF LATERAL AMYOTROPHIC SCLEROSIS AMONG THE POPULATION OF PENZA REGION

Ermolaeva Aleksandra Ionashevna, Doctor of medical sciences, head of sub-department of neurology and neurosurgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), neurology_mipgu@yandex.ru
Kovrygin Sergei Ivanovich, Student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), skovrygin@gmail.com

616.832.522

Background. The purpose of the study is to investigate clinical features of lateral amyotrophic sclerosis in Penza region.
Materials and methods. The survey of 20 patients was made. While diagnosing, the authors studied neurological, somatic statuses and carried out electromyography, biochemical tests of serum, cerebrum magnetic resonance scanning.
Results. As a result of the investigation the following features were detected. In 100% of cases a surgery preceded the debut of the disease. There are the geographic features of the disease’s distribution in the region with its maximum in the center and the East. The significant predominance of bulbar and cervicothoracic forms of amyotrophic lateral sclerosis was found. Electromyography showed the changes typical for the generalized process of muscles denervation due to motor neurons damage. Usage of rilutek in some cases was not effective.
Conclusion. The results of the present study show the features of lateral amyotrophic sclerosis in Penza region.

amyotrophic lateral sclerosis, features of the disease course, signs and symptoms.

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